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Christopher G. Engeland

Associate Professor
Director of the Stress and Immunity Lab
Department of Biobehavioral Health/College of Nursing

Contact Information

229 Biobehavioral Health Building
The Pennsylvania State University
University Park, PA  16802

Office: BBH 229, 814-865-4694
Lab: HHD 147, 814-863-2740

Research Interests:

I am interested in how stress, age, gender, and hormones affect immunity, inflammation, and health; also the feasibility of biomarkers for predicting health outcomes.  


i)  Effects of stress, age and sex on wound healing & inflammation (human, animal)
ii) Stress, inflammation and cognitive aging/decline (human)
iii) Hormonal regulation of dermal and mucosal tissue repair (human)
iv) Effects of chronic stress, morphine and oxytocin on wound healing (animal)
v) Biomarker and stress as predictors of preterm birth (human)
vi) Stress, inflammation, and obstructive sleep apnea (human)
vii) Salivary diagnostics (human)

Funded Research Projects

NIH R01 AG042595-01 (Engeland, Graham)                 09/30/2012 – 05/31/2018            $1,250,000
Inflammatory mediators of stress and cognitive aging
This longitudinal study incorporates blood and saliva sampling and a battery of psychosocial questionnaires (every 6 months for 4 years) into an ongoing prospective study that examines cognitive aging in 320 individuals 25-65 years of age in the Bronx, NY. Role: PI (Multiple)

Funded Research Projects

NIH R01 MD011575-01A1 (Giurgescu)                          01/06/2017 – 12/31/2021            $2,498,120
Social stressors and inflammation: A mixed methods approach to preterm birth
This mixed method, longitudinal study will be the first to prospectively examine five interrelated factors (social stressors, personal resources, emotional stress, cortisol, and inflammation) that have been related to preterm birth. The study will be conducted with 1500 African American women. Role: Co-I

Funded Research Projects

CTSI Bridges to Translation Award (Engeland)           11/01/2015 – 06/30/2017            $45,980
Penn State University
Hyperglycemia and impaired healing in medically complex surgical patients
This clinical pilot study examines hyperglycemia development and surgical outcomes in hernia repair patients, with a focus on lipidomics and proteomics aimed at factors critical for tissue repair that are assessed from blood and directly in the wound site (i.e., wound drainage). Role: PI